This is one of the more common food-drug reactions. Reprod Toxicol 2007;23:397-406. Lignans and flavonoids inhibit aromatase enzyme in human preadipocytes. Azrad M, Vollmer RT, Madden J, Dewhirst M, Polascik TJ, Snyder DC, Ruffin MT, Moul JW, Brenner DE, Demark-Wahnefried W. Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer. View abstract. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Pan A, Yu D, Demark-Wahnefried W, et al. View abstract. When considering the use of herbal supplements, seek the advice of your doctor. J Am Coll Nutr 1993;12:501-4. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The effect of flaxseed supplementation on body weight and ody composition: a systematic review and meta-analysis of 45 randomized placebo-controlled trials. View abstract. Flax is often sold as an herbal supplement. Curr Probl Cardiol 2022;47(7):100931. But before you take some, you decide to do some research on the interactions it may have with some of the medications you are currently taking. View abstract. de Deckere EAM, Korver O, Verschuren PM, Katan MB. View abstract. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Dietary phytoestrogens are not associated with risk of overall breast cancer but diets rich in coumestrol are inversely associated with risk of estrogen receptor and progesterone receptor negative breast tumors in Swedish women. All rights reserved. View abstract. Medicinal use of this product has not been approved by the FDA. See a medical center immediately if your reaction to flaxseed oil causes your throat to tighten or shortness of breath. To provide you with the most relevant and helpful information, and understand which View abstract. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. There is a problem with 2005 - 2023 WebMD LLC. View abstract. Colli MC, Bracht A, Soares AA, et al. View abstract. Clin Cancer Res 2005;11:3828-35. J Altern Complement Med 2020;26(9):799-806. View abstract. 2005-2023 Healthline Media a Red Ventures Company. Avoid using flax together with other herbal/health supplements that can also affect blood-clotting. View abstract. Eur J Nutr 2022;61(3):1377-1389. Saw palmetto Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin Clopidogrel Warfarin St. John's wort Review/update the Flaxseed oil doesnt have as many benefits as other omega-3 sources like fish, fish oil, and flax in its seed form. Mol Nutr Food Res 2009;53:1366-75. Do not use more of this product than is recommended on the label. View abstract. Cotterchio M, Boucher BA, Manno M, et al. JAMA Pediatr. The use of flax seeds or flaxseed oil may result in lowered blood sugar. View abstract. Flaxseed in lupus nephritis: a two-year nonplacebo-controlled crossover study. Other uses not proven with research have included enlarged prostate, heart disease, constipation, high blood pressure, irritable bowel syndrome, menopausal symptoms, weight loss, diverticulitis, attention deficit-hyperactivity disorder (ADHD), cancer (prostate, breast, lung, endometrial), and others. J Med Food 2012;15:840-5. Some medications that may interact with flaxseed oil negatively include: those that alter your blood flow and bleeding, including: aspirin blood thinners, like warfarin (Coumadin) and. Medications are the primary treatment for hypertension; however, adherence to drug regimens is low (~50 %). Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity: a controlled, crossover trial. Cockerell KM, Watkins AS, Reeves LB, et al. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. Keep in mind the FDA does not recommend Trulicity as a "first-line therapy" for . Bierenbaum ML, Reichstein R, Watkins TR. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Research is strongly showing that long-term use of metformin and at high doses (1.5mg or higher daily) can deplete levels of vitamin B12. Because of the potential for flaxseed oil side effects and drug interactions, you should talk to your primary care provider before regularly supplementing your diet with the plant oil. We comply with the HONcode standard for trustworthy health information. Mohammadi-Sartang M, Mazloom Z, Raeisi-Dehkordi H, Barati-Bodaji R, Bellisimo N, Totosy de Zepetnek JO. Rich in omega-3 fatty acids, flaxseed oil is gaining ground as a functional food with many potential health benefits. Flaxseed oil may be rich in omega-3 fatty acids, but it may not be the right type. Flaxseed: a potential treatment for lupus nephritis. View abstract. Pan A, Demark-Wahnefried W, Ye X, et al. are using nonsteroidal anti-inflammatory drugs. To be as proactive as possible, consult your doctor about using flaxseed oil as a dietary supplement before you begin to use it. You should see your doctor immediately if you suspect youre having a reaction from the intake of flaxseed oil. Though tiny, they are rich in the omega-3 fatty acid ALA, lignans and fiber, all of which have been shown to have many potential health . Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study. Our website services, content, and products are for informational purposes only. Accessed Sept. 27, 2017. https://nccih.nih.gov/health/flaxseed/ataglance.htm. Ibrgger S, Kristensen M, Mikkelsen MS, Astrup A. Flaxseed dietary fiber supplements for suppression of appetite and food intake. Flax is the seed of a plant called Linum usitatissimum, and is also known as Flax Seed, Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Flax, Echter Lein, Flachssamen, Flax Hull, Flax Lignans, Gemeiner Flachs, Graine de Lin, Kattan, Keten, Leinsamen, Lignans, Lin, Olagineux, Lin Textile, Linaza, Lini Semen, Linho, Lino, Linseed, Lint Bells, Linum, Malsag, Phytoestrogen, Ta Ma, Tisii, Winterlien, and other names. View abstract. Am J Clin Nutr 1999;69:395-402. Am J Clin Nutr 2009;90:288-97. J Nutr 2010;140:1937-42. (2013). This article explores 6 potential health benefits of flaxseed oil, plus how to use it. Lucas EA, Wild RD, Hammond LJ, et al. Hashempur MH, Homayouni K, Ashraf A, Salehi A, Taghizadeh M, Heydari M. Effect of Linum usitatissimum L. (linseed) oil on mild and moderate carpal tunnel syndrome: a randomized, double-blind, placebo-controlled clinical trial. Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. 2016 Jun;35(3):615-25. Flaxseed (Linum usitatissimum L.) oil processing and selected products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Accessed Sept. 27, 2017. Because flaxseed oil might decrease blood clotting, stop using flaxseed oil two weeks before having elective surgery. View abstract. Mohammadi-Sartang M, Sohrabi Z, Barati-Bodaji R, Raeisi-Dehkordi H, Mazloom Z. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. View abstract. Hemodial Int. 2014;22:43. Suzuki R, Rylander-Rudqvist T, Saji S, et al. Flax seed oil is used to treat the following conditions: Atopic Dermatitis; Constipation; Eczema; High Cholesterol; Peripheral Neuropathy; Prostate Cancer; green tea. Ann Nutr Metab 2000;44:263-5. Some people use black seed oil supplements to treat certain health conditions, including arthritis, allergies, asthma, and diabetes, and maintain a healthy weight. Int J Cancer 2006;119:925-31. Flaxseed is a commonly recommended and used dietary supplement today. But what you might not realize is that flaxseed contains very large amounts of lignans and phytoestrogens, making it one of the most estrogenic foods around. Arjmandi BH. View abstract. Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells. An open-label study on the effect of flax seed powder (Linum usitatissimum) supplementation in the management of diabetes mellitus. Drugs. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Cats require certain vitamins, minerals, and . Diabetes drugs. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. 2019;38(7):1961-1969. 2013 Apr;17(2):275-81. Flaxseed and prostate cancer risk. One tablespoon of flaxseed oil has 7.26 grams. However, it requires a steady dose of essential nutrients, which must come from food or supplements, in order to function at its best. 1995;49(3):169-178. Haghighatsiar N, Askari G, Saraf-Bank S, Feizi A, Keshmiri H. Effect of flaxseed powder on cardiovascular risk factor in dyslipidemic and hypertensive patients. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. J Nutr. Not all possible interactions are listed in this product guide. Yari Z, Rahimlou M, Poustchi H, Hekmatdoost A. Flaxseed supplementation improves anthropometric measurements, metabolic, and inflammatory biomarkers in overweight and obese adults. Research on the use of flaxseed and flaxseed oil for specific conditions shows: When used in combination with daily exercise and a low cholesterol diet, flaxseed might help control cholesterol levels. Certain herbal supplements, such as St. John's wort, may decrease blood levels of some statin drugs, and when taken with atorvastatin, may . Eur J Clin Nutr 2007;61:1423-8. Yes, several popular herbal supplements can impact the effectiveness of apixaban (Eliquis), rivaroxaban (Xarelto), betrixaban (Bevyxxa), and other anticoagulant drugs (blood-thinners) classified as direct factor Xa inhibitors. are using cholesterol-lowering drugs. 4. Common interactions include back pain among females and flushing among males. View abstract. Flaxseed and flaxseed oil. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in postmenopausal women. February 23, 2023. Menopause 2006;13:631-42. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. View abstract. Appl Physiol Nutr Metab 2009;34:89-98. View abstract. Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh Y. (n.d.). Wang L, Chen J, Thompson LU. Flaxseed oil contains a-linolenic acid (ALA), which the body can break down into an omega-3 fatty acid. View abstract. include protected health information. does flaxseed interfere with blood pressure medication Master, I m hungry. We avoid using tertiary references. Sun J, Bai H, Ma J, et al. But it can interfere with the absorption of some medications and supplements.Take oral agents one hour before -- or two hours after -- flaxseed to prevent decreased absorption. Can increase. A September 2014 article published in the Journal of Food Science and Technology says flaxseed oil is the best plant source of the essential fat. Prasad K. Dietary flax seed in prevention of hypercholesterolemic atherosclerosis. No related drugs found for this medication. View abstract. Bloedon LT, Szapary PO. Hailshadow/Getty Images. Accessed Sept. 27, 2017. View abstract. Possible side effects include: Diarrhea and loose stools Worsening constipation 1 These side effects can be minimized by taking flaxseed oil with plenty of water and by taking it at recommended doses. This will help prevent any negative reactions that might arise. information is beneficial, we may combine your email and website usage information with A high dose of flaxseed reduces the production of pro-inflammatory eicosanoids such as thrombozane A2 and other lipids mediators like platetet-activating factor (PAF). This might alter the effects of flaxseed. Sardines - bone loss, joint pain. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition. A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk. Just 500 Extra Steps a Day Can Lower Heart Disease Risk in Seniors, Study Suggests . View abstract. Do not take this medication for more than 7 days unless directed by your doctor. Fish oil may be a better and safer choice. Fatty acids and lignans in unground whole flaxseed and sesame seed are bioavailable but have minimal antioxidant and lipid-lowering effects in postmenopausal women. J Nutr 2010;140:293-7. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. J Am Coll Nutr 2008;27:65-74. Most of the animal studies have focused on breast cancer. Adlercreutz H, Fotsis T, Bannwart C, et al. Many people take fish oil supplements daily, but you may not know whats the right dosage for you. Flaxseed consumption may reduce blood pressure: A systematic review and meta-analysis of controlled trials. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Dietary fat and prostate cancer: current status. Flaxseed is considered to be a goitrogen. Nutr Cancer 2007;58:162-70. The effects of dietary flaxseed on cardiac arrhythmias and claudication in patients with peripheral arterial disease (1). A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Would you believe hundred grams of flaxseeds contain 813 mg of potassium. What medications does flaxseed interfere with? Other drugs may interact with flax, including prescription and over-the-counter medicines, vitamins, and herbal products. Fish Oil Dosage: How Much Should You Take Per Day? Obes Facts 2022. Arerugi. (2016). Flax may also be used for purposes not listed in this product guide. View abstract. View abstract. If we combine this information with your protected Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Meta-analysis of the effects of flaxseed interventions on blood lipids. Ramon JM, Bou R, Romea S, et al. View abstract. Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen. J Steroid Biochem Mol Biol 1992;41:615-9.. View abstract. J Natl Cancer Inst 1993;85:1571-9. View abstract. Click here for an email preview. Lemay A, Dodin S, Kadri N, et al. 2019;29:41-48. Clin Cancer Res 2004;10:7703-11. View abstract. The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Things to remember when you fill your prescription. Sorry, we have no data available. You may also want to be careful combining flaxseed oil and warfarin, which is a blood-thinning medication that prevents the formation of blood clots. Circulating enterolactone and risk of endometrial cancer. The effects of flaxseed dietary supplement on lipid profile, bone mineral density, and symptoms in menopausal women: a randomized, double-blind, wheat germ placebo-controlled clinical trial. Brooks JD, Ward WE, Lewis JE, et al. Flaxseed. View abstract. Flaxseed oil doesn't have these phytoestrogens. Leitzmann MF, Stampfer MJ, Michaud DS, et al. View abstract. Goss PE, Li T, Theriault M, et al. It's most often used for constipation (a common hypothyroid symptom) and touted for many other supposed health benefits. 2016 Jun;67(4):461-9. View abstract. Cancer Causes Control 2008;19:259-72. Please contact your doctor or pharmacist. Nutr Rev 2004;62:18-27. The use of flax seeds may increase your chances of bleeding. The phase IV clinical study analyzes what interactions people who take Flaxseed and Metformin have. View abstract. Cancer Epidemiol Biomarkers Prev 2000;9:719-25. Koizumi Y, Arai H, Nagase H, Kano S, Tachizawa N, Sagawa T, Yamaguchi M, Ohta K. [Case report: anaphylaxis caused by linseed included in baked bread]. View abstract. A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. You may be eager to find a supplement to boost the omega-3 fatty acids in your body. Flaxseed oil is an oil made from pressed, ground flaxseeds. View abstract. Demark-Wahnefried W, Polascik TJ, George SL, et al. Some people also take flaxseed to treat inflammatory diseases. Dietary phytoestrogens and lung cancer risk. Do not take flax without medical advice if you are using any of the following medications: any medications for diabetes or high blood pressure; This list is not complete. Serraino M, Thompson LU. Taylor, C. G., Noto, A. D., Stringer, D. M., Froese, S., and Malcolmson, L. Dietary milled flaxseed and flaxseed oil improve N-3 fatty acid status and do not affect glycemic control in individuals with well-controlled type 2 diabetes. Flaxseed oil may cause complications with women who are pregnant because of its ability to affect hormones. National Center for Complementary and Integrative Health. View abstract. Patade A, Devareddy L, Lucas EA, et al. How fast does psyllium work? View abstract. Omega 3 dietary sources include flax seeds, chia seeds, walnuts, and fish. Nutr Metab (Lond) 2021;18(1):91. Thompson LU, Rickard SE, Orcheson LJ, Seidl MM. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Dietary flaxseed independently lowers circulating cholesterol and lowers it beyond the effects of cholesterol-lowering medications alone in patients with peripheral artery disease. Monitor your blood sugar closely. Store at room temperature away from moisture and heat. You should also discuss the length of time its healthy to use it as well as a recommended dosage. Flaxseed oil drug interactions may also improve the effectiveness of some medications, notes Mount Sinai, including nonsteroidal anti-inflammatory drugs and prescription medications that lower blood cholesterol. Herb-Drug Interactions Milk thistle is an inhibitor . View abstract. information highlighted below and resubmit the form. Flaxseed is packed with beneficial nutrients, omega-3 fatty acids, and fiber. View abstract. 2020:1-9. Selected from data included with permission and copyrighted by First Databank, Inc. However, because antibiotics kill these bacteria, lignans might not be formed as usual. While some studies support health claims, most are small, and more research is needed. Vitamin Keven in foods such as kale, lettuce, broccoli, and chickpeascan counteract a blood thinner's benefits. View abstract. There is conflicting research about whether ALA found in flax seeds and flaxseed oil actually causes tumors from prostate cancer to be more aggressive. Stress: Stress, especially high levels of stress and anxiety, has been shown to lower and breakdown HRT at a quicker rate. List Flaxseed side effects by likelihood and severity. Teas have been used as a natural remedy to soothe stomach upset for thousands of years. View abstract. 2021;60(1):287-298. We'll take a look at just what makes hemp oil beneficial and which conditions may improve from. Getting omega-3 into your body requires eating it in your diet or consuming it as a supplement, as your body does not produce it on its own. 016 Sep 1;21:70. J Nutr. Ann N Y Acad Sci 1990;595:281-90. JAMA 2005;294:1493-1504. Reducing atherogenic risk in hyperlipemic humans with flaxseed supplementation: a preliminary report. View abstract. Khan G, Penttinen P, Cabanes A, et al. Is Flaxseed Good for Thyroid? Am J Clin Nutr 2003;77:783-95. View abstract. Eur J Nutr. Variability in anticancer lignan levels in flaxseed. Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study. Research suggests that hemp oil has health benefits. Here are 9 teas that help treat stomach problems. ", Kardiologia Polska: "Linseed Oil Increases HDL3 Cholesterol and Decreases Blood Pressure in Patients Diagnosed With Mild Hypercholesterolaemia", Phytotherapy Research: "A Comparison Between the Effects of Flaxseed Oil and Fish Oil Supplementation on Cardiovascular Health in Type 2 Diabetic Patients With Coronary Heart Disease: A Randomized, Double-Blinded, Placebo-Controlled Trial", U.S. National Library of Medicine: "Warfarin". However, research has shown that flax may not be effective in treating this condition. It is also used for many other conditions, but there is no good. OTHER NAME(S): Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Fl, Flax (Linum usitatissimum) is a food and fiber crop. Exp Biol Med (Maywood) 2007;232:1071-80. View abstract. This includes angelica (dong quai), capsicum, clove, danshen, garlic, ginger, ginkgo, horse chestnut, panax ginseng, poplar, red clover, saw palmetto, turmeric, and willow. Adlercreutz H, Heikkinen R, Woods M, et al. Asia Pac J Clin Nutr. According to Dr. Jaiswal, some of the common prescription and over-the-counter medications that interact with levothyroxine are: Antibiotics: ciprofloxacin, rifampin Seizure medications: phenytoin, fosphenytoin, and carbamazepine Antidepressants: amitriptyline, fluoxetine 2014 Jul;63(7):945-50. People use flaxseed and flaxseed oil to reduce cholesterol and blood sugar and treat digestive conditions. Taking flaxseed along with diabetes medications might cause blood sugar to drop too low. Check your medications for potential interactions with herbal supplements Popular Interaction Pages. Answer: Atorvastatin (Lipitor), rosuvastatin (Crestor), and other cholesterol-lowering statin drugs can be affected by taking supplements and can affect your ability to absorb certain vitamins and minerals. Khalesi S, Irwin C, Schubert M. Flaxseed consumption may reduce blood pressure: a systematic review and meta-analysis of controlled trials. 2017 Sepl18(9):1096-1107. View abstract. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023 . Int J Vitam Nutr Res. Generic name: flax (FLACKS) The phase IV clinical study analyzes what interactions people who take Flax seed and Aspirin have. Furthermore, some blood thinners, NSAID pain killers, hormone treatments, and certain medications for blood pressure, cholesterol, and diabetes may interact with flaxseed oil and flaxseed. J Am Coll Nutr 2010;29(1):72-80. Flaxseed and cardiovascular risk factors: results from a double blind, randomized, controlled clinical trial. Nesbitt PD, Lam Y, Thompson LU. Bodybuilder Darwin Uribe Will Withdraw From 2023 Arnold Classic. The beneficial potential of flaxseed to reduce blood pressure (especially diastolic blood pressure) may be greater when it is consumed as a whole seed and for a duration of >12 wk. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. Yang C, Xia H, Wan M, et al. 2020;152:104622. View abstract. The relatively few animal studies addressing other cancers have shown some . Khalesi S, et al. Eating a flaxseed muffin daily for 3 months or taking flaxseed powder by mouth daily for 2 months seems to reduce breast pain that occurs at the start of the, Obesity. View abstract. Though your body can make many types of fat on its own, such as cholesterol, omega-3 fatty acids are essential and must be supplied from outside sources. Excess sodium disturbs the water. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dietary phytoestrogen intake is associated with reduced colorectal cancer risk. J Investig Allergol Clin Immunol. Complement Ther Med. Moreover, the National Center for Biotechnology Information shared an article from the Division of Natural Products, which is a branch of the Food and Drug Administration, agreeing with the dangers that flaxseed can have on the . Cunnane SC, Hamadeh MJ, Liede AC, et al. Blood pressure drugs, herbs and supplements. Learn about the medical uses, claims, and side effects of flaxseed. Edel AL, Rodriguez-Leyva D, Maddaford TG, Caligiuri SP, Austria JA, Weighell W, Guzman R, Aliani M, Pierce GN. PAF is an active compound in the body that is related to a variety of immunological reactions. Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients. Fitzpatrick says new research also suggests significant blood pressure-lowering effects of flaxseed. Learn about the medical uses, claims, and side effects of flaxseed. [3] . Ursoniu S, Sahebkar A, Andrica F, Serban C, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration Group. J Am Coll Nutr 2001;20:143-8. Effects of Vitex agnus and flaxseed on cyclic mastalgia: a randomized controlled trial. Other drugs may interact with flax, including prescription and over-the-counter medicines, vitamins, and herbal products. View abstract. Rhee Y, Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. View abstract. Int J Food Sci Nutr. Learn about the medical uses, claims, and side effects of flaxseed. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways. Written by Cerner Multum. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. https://naturalmedicines.therapeuticresearch.com. Am J Clin Nutr 2004;80:204-16. Examples of barbiturates and medications that have barbiturate actions include: Felbatol (felbamate) High dose flaxseed oil supplementation may affect fasting blood serum glucose management in human type 2 diabetics. Can J Physiol Pharmacol. Bongartz U, Hochmann U, Grube B, et al. 2021;75(1):99-111. While over-the-counter drugs can help relieve constipation, natural remedies like flaxseed have proven to be effective in some people. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Morshedzadeh N, Rahimlou M, Shahrokh S, Karimi S, Mirmiran P, Zali MR. Flaxseed - More Interactions. Wang Wuyu suddenly woke up and sat up, his stomach made a loud noise like a drum beating. NSAIDs: NSAIDs are a term used for non-steroidal anti-inflammatory drugs such as ibuprofen; which when taken with HRT can decrease its ability to protect your heart. Read More Created for people with ongoing healthcare needs but benefits everyone. Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN. View abstract. https://naturalmedicines.therapeuticresearch.com. Epiandrosterone . Caligiuri SP, Aukema HM, Ravandi A, Guzman R, Dibrov E, Pierce GN. Avoid using flax together with other herbal/health supplements that can lower blood sugar, such as alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others. Copyright 1996-2023 Cerner Multum, Inc. However, when taken in large amounts and with too little water, flaxseed can cause: Avoid use of flaxseed and flaxseed oil during pregnancy. Flaxseed interacts with 583 drugs . If you take insulin or other medication for diabetes, consult your physician before consuming flaxseed meal. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Br J Cancer 2008;98:636-40. Brouwer IA, Katan MB, Zock PL. Certain antibioticsspecifically quinolone antibiotics (like Cipro) and tetracycline antibiotics (like Achromycin and Sumycin)interact with zinc in the gastrointestinal tract and don't allow the. Brand names: Flax Seed Oil, Flax Oil View abstract. Plasma phytoestrogens and subsequent breast cancer risk.