Common Methimazole side effects: Drug ineffective: 348 reports Hyperthyroidism (over activity of the thyroid gland): 336 reports Fatigue (feeling of tiredness): 320 reports Weakness: 271 reports Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 262 reports Headache (pain in head): 252 reports I should have listened to him. Slowly weaning off or tapering to the right dose is the best method. ", Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Your healthcare provider will check your thyroid levels and adjust your dose as needed. A relatively low dose of Methimazole was prescribed, along with Lisinopril, and Metoprolol. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Talk to your doctor about these issues, as they can be the effects of your thyroid hormone levels getting back to normal. Not taking your medication also increases your risk of fatal conditions like myxedema coma if you are hypothyroid, and thyroid storm if you are hyperthyroid. I want to know if I should see another doctor. His goal is to wean me off very slowly. Skip the missed dose if it is almost time for your next scheduled dose. Thank you so much! 2023 Dotdash Media, Inc. All rights reserved, Mary Shomon is a writer and hormonal health and thyroid advocate. Anterior cervical discectomy, no fusion - what to expect? Hello, what you think of my lab results & should I see another doctor? This was very irresponsible of them and I was not able to be well enough to work for a year after that. And other symptoms of hypothyroidism. While you may experience some symptoms of overactive thyroid more than others, and you may even consider some of them beneficial, it is important to be aware of the strain this condition is putting on your heart, bones, and overall health. appropriate medical assistance immediately. Do not use methimazole in larger or smaller amounts or for longer than recommended. Thanks, THANKS FOR YOUR HELP LET ME KNOW IF YOU THINK OF ANYTHING. No chance of a beach here. The anxiety and the eye problem could be symptoms of Hyperthyroid, or it might be unrelated. Because I thought they might be responsible for lowering TSH. Methimazole is used to treat hyperthyroidism, a condition that occurs when the thyroid gland produces too much thyroid hormone. Methimazole doses are based on weight in children, and any changes may affect your child's dose. The doctor told me to take a Metoprolol once in the morning, then, around lunch time, take the 20 mgLisinopril, then, at dinner time, take another Metoprolol. As soon as they see that youre going hyper again, they should put you back on your regular dose. If your levels start to drop toward the lower end of the scale, you'll be able to taper the dose down a bit - to 20 mg a day. I have been taking the same dosages for all those years, except my dosage for Methimazole was brought down to 1 and 1/2 pills (5 mg pills) about a year ago. Thank God for my good health again. Hi, Sounds like your doctor wants to work with you though if he gave you that choice. I was taken to jail where I was geld for two weeks without my medicine and let me tell you I got sick with peripheral edema, vasculitis. https://patient.info/forums/discuss/stopping-methimazole-543742. Twice, I got worried because my hand and arm were deep red from the tightness of the cuff. I would ask to do labs again. It was the Acetyl-L-Carnitine that really worked for me and from other boards seems to work for Graves patients. It is also used before thyroid surgery or radioactive iodine treatment. Call your doctor for medical advice about side effects. I have my test results and I am taking 15MG Methimazole a day since 5/25 and the Endo told me to continue taking the same dosage Hi, Then later when I added supplements and my lab tests were improving very quickly, my new Endo would decrease my dose by no more than 2.5 mg at a time. You may report side effects to FDA at 1-800-FDA-1088. The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life. Thyrotoxic Crisis Oral Some clinicians recommend 60-80 mg daily. Methimazole is used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. We offer this Site AS IS and without any warranties. 19 users are following. Metroprolol is a beta blocker that slows the heart rate. 2. It is generally well tolerated and has few side effects, but it does require close monitoring because of a low rate of some severe side effects, such as low blood counts. Methimazole is an antithyroid medicine. You may need a different medication or a dose adjustment, but you should never quit your medication without your doctor's approval. So I don't think there is one size fits all but I do believe you need the information from the tests your doc does as well as learning about your body and its symptoms and what works and what doesn't in order to get well. I started out at 30mg a day. Severe hyperthyroidism: 60 mg orally per day. What are the medication for hypothyroidism in cats? Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. I was on 5 mg once a day. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. My body symptoms were freezing weak cold tired muscles and bones hurt. But it can also cause weight loss and a reduced need for sleep, which some people actually welcome. My methimazole was 5 mg once a day. Generic name: methimazole [me-THIM-a-zole] Thyroid level saga continuespart 20. Clearly, there are sensible health reasons to take your prescribed thyroid medication. Typical dosing for methimazole The dose of methimazole for adults ranges from 5 to 40 mg by mouth per day depending on how severe your hyperthyroidism is. Coming off of Klonopin after 8 monthswhat to expect and how to do so, Graves Disease/hyperthyroid & I experience Hypnagogic hallucinations-anyone with similar experie, Thyroid Removal Effects and Graves Disease. Same as sudden weather changes, we get headaches etc. We offer this Site AS IS and without any warranties. methimazole - UpToDate One thing my Endo and I agree on is that he will not stop a patient's medication entirely unless their antibody levels are within the normal range even if all their thyroid labs are normal. That is a real challenge but I know one lady with both Graves and Hashi's who got treated by a Naturopath who was able to keep her thyroid levels normal with just the natural methods. I feel fine. 2 days on, one day off and this past week my endocrinologist gave me the choice of either going right off Tapazole or going off it slowly. decreased sense of taste. It becomes too easy to label them as septic, and we may forget that endocrinologic emergencies, specifically thyroid storm, can present in very much the same way. Long-term methimazole therapy improves Graves disease - MDedge Each time I reduce, my TSH elevates- but my T3 stays within range which is what my endo focuses onand it does take about six weeks for my body to adjust to the lower dosebut it does adjust. Homeopathic remedy for overactive thyroid, Graves' Disease: Symptoms, Treatment And Complications, Graves' Disease: Symptoms, Diagnosis And Treatment, Holistic Approach to Thyroid Related Problems: Naturopathic Medicine for Thyroid Disease. Not all possible interactions are listed in this medication guide. How Are Thyroid Disorders Linked To An Increased Risk Of Developing Osteoporosis? What dose were you on to start with? (PTU), Methimazole, or Tapazole thyroid medicine 4 days before their tests. Two-step method for administration: Test dose: 0.5 to 1 mg as slow IV push administered over 10 minutes Subsequent doses: 1 to 3 mg IV over 10 to 15 minutes every few hours to desired effect with monitoring of cardiac rhythm Esmolol can be considered as an alternative agent They took blood work and X-rays, and this went on for over 4 hours. I've read of people getting off Methimazole all at once and doing okay, although many do have "withdrawal" symptoms (symptoms of being hyper) as their body purges the medication. (unknowingly had covid at the time of last bloodwork). The ENT in the group did suppression therapy. My GP suggestd similar action as my TSH levels started rising (only just out of range)and my FT4 dropped. I'm on 2.5mg sun, we'd, Friday I was stressed about some things before. Swollen hands, feet, and face. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. But I was stressing about some dumb things before. Dr. Fereidoun Azizi. I have nevery had anxiety attacks before. Her overall presentation does not seem to add up in being secondary to urosepsis. Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals. Then I tried one 500 mg capsule and saw how I felt on it beofre I raised it to the dose that was mentioned in the research article. Im so confused. There are a number of strategies you can use toremember to take your thyroid medication. You should not use methimazole if you are allergic to it, or: To make sure methimazole is safe for you, tell your doctor if you have: Using methimazole during pregnancy could harm the unborn baby. But don't tapper too much and too fast. T3 total: 332; FT3 11.1; FT4 387, TSH <.005. I'm very upset because I figure he's the doctor and shouldn't have left that choice up to me. Some clinicians recommend discontinuing methimazole 2-7 days before radioactive iodine; may restart methimazole 3-7 days after radioactive iodine, then generally taper over 4-6 weeks as thyroid function normalizes and radioactive iodine becomes effective. What many people don't realize is that there are quite a few symptoms that can apply to either/both hyper and hypo. If you are on a beta blocker for your heart rate (propranolol, atenolol, metoprolol, etc), your doctor may discontinue, decrease the dose, or keep the dose the same with plans to wean the medication in the weeks and . Thyroid Storm: Treatment Strategies - ALiEM And then see if you need the beta blocker if what you're experiencing is heart palpitations/shakiness. Always speak to your doctor before acting and in cases of emergency seek We aim to disrupt how medical providers and trainees can gain public access to high-quality, educational content while also engaging in a dialogue about best-practices in EM and medical education. If you have thyroid disease and don't take your prescribed medications to manage it, you can have a number of serious long-term effects. There may be two explanations for this benefit of long-term therapy, according . Went back to 10mg, after 2 consecutive blood tests were good (12 weeks) and then went to 7.5, just did a another 12 week stint, all is good so went to 5 mg this week (very happy). I also wanted to know my Carnitine levels before I started taking it so I asked my doc to give me a requisition to get it tested and found I was deficient. Going off methimazole - Thyroid Disorders - MedHelp I am a 52 year old female and I had been on 15MG Methimazole for the over 2 months and my Endo lower the dosage to 10MG (took the And I vote you find another endo even if you do even out - you want someone who knows their stuff to monitor you in case you relapse in the future. She seems relatively anxious on physical exam, and you note that she is diaphoretic. So I would gradually reduce until you think you can go cold turkey. What Do Herpes Sores Look Like at Different Stages. HyperT77 My Endocrinologist has started weaning me off of Methimazole. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Thyroid medication can be expensive and can sometimes cause undesirable side effects, especially in the first three months of treatment. I do have Hashitoxicosis so I remember you saying that I won't respond as well to methimazole. any responses appreciated thx Lauren, If you go off tapazole cold turkey you can go into a thryoid storm and possibly die it happened to me I had dry heaves bad thank god I made it through the night. Furthermore, you should fully understand the consequences of untreated thyroid disease. I am also trying to wean off and am having really really really bad anxiety is this normal???? I dont think theres any harm in that as long as they are testing your blood frequently like every month. The first time my Endo told me to decrease my dose from 10 mg to 5 mg, about 2 weeks after I did that I got a rebound effect of symptoms so I raised it by 2.5 mg and told her. Methimazole can pass into breast milk and may harm a nursing baby. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Instructions for Women Pregnant women cannot receive the therapeutic radioactive iodine, since it will harm the fetus. Unfortunately, there isn't a natural or herbal replacement for thyroid hormone. My current doctor, who is new to me, also wanted to wean me off but she tested my antibodies first. Or, you could be experiencing over-treatment, meaning that you need a dose adjustment or a different medication. Patient is a UK registered trade mark. When I was in the ER, they hooked me up to the BP cuff, and it stayed there, turning off and on the entire time. Endocrinologic emergencies often fall at the wayside and are not generally considered as a possible diagnosis up front in patients in the emergency department who meet the criteria for systemic inflammatory response syndrome (SIRS). You must tell us if you are pregnant, even if you Unusual weakness or fatigue, fever, headache, skin rash, muscle or joint pain, loss of appetite, pain, tingling, or numbness in the hands or feet. It works by making it harder for the body to make thyroid hormone. When I asked if my numbers should have been closer to hypo range if I was a candidate for remission, she said yes but wanted to see if I could wean off anyway. "Long-term, low-dose methimazole treatment for 60-120 months is a safe and effective treatment for Graves hyperthyroidism and is accompanied by much higher remission rates than the usual 18-24 months of methimazole treatment," he summarized. I take 5 mg at night and 2.5 in the morning. I was on 10mg (5mg x 2)a day Carbimazole. Are these symtpoms of both hyper and hypo? Best, Rachel. Gimel is right, it only has a 6 hour half life. rachelemacd Now I am in none. Version: 4.01. By using this Site you agree to the following, By using this Site you agree to the following, The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life. If you want to get notified by every reply to your post, please register. I don't get it. 6 years ago, Medically reviewed by Drugs.com on Feb 20, 2023. Your story is exactly like mine. Do not take extra medicine to make up the missed dose. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Upgrade to Patient Pro Medical Professional? Methimazole prevents the thyroid gland from producing too much thyroid hormone. first cutting the 5mg tablet in half then in 1/4's. She enjoys giving lectures and writing articles for both the lay public and medical audiences. We comply with the HONcode standard for trustworthy health information. Have been on it for 18 months. TSH above 1 is a good place to be in according to my endo. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. The primary mechanism of action of methimazole is to block thyroid hormone production from the thyroid gland. Weaning off of Methimazole.. What next? - MedHelp Brand names: Tapazole, Northyx HI, I was diagnosed with Graves Disease last fall (2016). You should not breast-feed while using methimazole. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. I never was given clarity about what "the damage" entailed though:(. The maintenance dose is 5 to 15 mg per day. Hypothyroidism (underactive thyroid). If someone else had been through this I'd certainly like to know their opinion. I did this (decided to lessen the dose) all by myself with a naturopath's advice (my "specialist" seems to have forgotten about me and never did the follow up in mid-March, and I am not disappointed =;) The biggest help has been to deal with my stress. Didn't find the answer you were looking for? And I am still could thins be a side affect of relapse or not taking my meds? Thats what Im saying. My pcp didn't like that. I refused to take blood pressure the whole time. Can You Eat Soy If You Have a Thyroid Condition? These side effects usually mimic the side effects of hypothyroidism, because if you stop taking your medication your body will not be able to produce it naturally for some time. Natural Solutions For Graves' Disease & Hashimoto's Thyroiditis. I just wanted to tell everyone DON'T GIVE UP and DON'T TAKE THE RADIATED IODINE or have your thyroid removed (unless there is a growth of course). Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Initial dose: Mild hyperthyroidism: 15 mg orally per dayModerately severe hyperthyroidism: 30 to 40 mg orally per daySevere hyperthyroidism: 60 mg orally per day Maintenance dose:5 to 15 mg orally per day Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervalsUses: -For the treatment of Graves' disease with hyperthyroidism or toxic multinodular goiter in whom surgery or radioactive iodine therapy is not an appropriate treatment option.-To ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. IS THERE A WEIGHT LOSS PLAN THAT ADDRESSES THYROIDECTOMY - what do you do to lose weight? I am not so familiar with hyper as I am hypothyroidism; however, since Methimazole only has a half life of 4-6 hours, it clearly is a fast acting med, similar to a T3 med for hypo. 0.84 t4 sounds pretty low so maybe that was part of the decision? Vancomycin Loading Doses in Pediatric Patients: A Missed Opportunity? Stop using methimazole and call your doctor right away if you have signs of infection such as: Some my symptoms inc My thyroid was stable for about 4 years, then suddenly, after my Mom's death, my thyroid went into hypothyroid. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. I feel wonderful now. even my hair started falling out and to me to be a woman and have your hair fall out is the worst thing in the world. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. ALiEM is your digital connection to the cooperative world of EM. Side effects are also most likely to occur within the first three months of treatment, so keep that in mind if you are beginning a new regimen.
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